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The ease of rapid genotyping coupled with massive phenotyping (such as measuring gene expression
simultaneously across tens of thousands of gene) presents an exiting challenge for evolutionary
statistical genomics. By developing and deploying tools for linking genetic variation with agronomic
or medical phenotypes of interest, my group hopes to help experimental geneticists identify genomic
regions, genes, and specific mutations underlying complex traits. Several statistical problems that
arise in this endeavor include: detecting cryptic population structure in samples of cases and
controls, multiple testing from scanning many markers and many phenotypes, and disentangling correlations
due to shared regulatory networks of co-regulated genese.
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